Those age 70 and older had the highest incidence of heart attack and heart disease of any age group, the researchers said. Statins reduce levels of LDL-cholesterol, the so-called 'bad' cholesterol, by inhibiting an enzyme called HMG-CoA-reductase (HMGCR). "Cholesterol-lowering medications are affordable drugs that have reduced risk of heart disease for millions of people worldwide, but until now their benefits for older people have remained less certain," study co-author Dr. Marc S. Sabatine said. "Taken together, these results suggest that inhibiting HMGCR with statins may help reduce cancer risk though non-lipid lowering mechanisms, and that this role may apply across cancer sites," Carter says. Meanwhile, an analysis of 29 studies involving more than 244,000 adults found that cholesterol-lowering therapies were associated with a reduction in the incidence of all cardiovascular events, including death, heart attack and stroke, researchers at Brigham and Women's Hospital in Boston reported. Younger women at higher risk for death after heart attack, Some psoriasis meds may also help prevent heart disease, Statins cut heart attack, stroke risk even in older adults, study says. Nov. 10 (UPI) --Older adults benefit at least as much as young people from cholesterol-lowering medications that reduce the risk of heart attack, stroke and heart disease, according to two … "This effect may operate through other properties of statins, including dampening down inflammation or reducing other chemicals produced by the same cellular machinery which synthesizes cholesterol.". The drugs lowered the risk for these heart-related health events by 15% for every one-point reduction in LDL cholesterol among people age 75 and younger, according to the researchers. These medications are currently taken by 1 in 4 people, making them the … Mendelian randomization assesses associations between genetically predicted levels of a risk factor and a disease outcome, in order to predict the extent to which that risk factor causes the outcome. This document is subject to copyright. Over a follow-up period of up to four years, 10 percent of those who discontinued their statins … "With the proportion of people living beyond 70 years of age worldwide rapidly increasing, [there is] huge potential for ... strategies aimed at lowering LDL cholesterol levels," said Nordestgaard, a clinical professor of genetic epidemiology at Copenhagen University Hospital in Denmark. "Statins are very effective at lowering LDL cholesterol [preventing it from developing into plaque that deposits on blood vessel walls]. People taking dummy pills and statins experienced similar side effects in a new study. Despite the large sample size of more than 360,000 participants and the broad set of outcomes analyzed in this study, the team adds that there are a number of limitations to this work. We decided to assess the potential effect of statin therapy on cancer risk using evidence from human genetics.". Statins News - Statins Information. Your feedback will go directly to Science X editors. Statins are also very effective at stabilizing the plaque that is already there, and are extremely effective at lowering the … But evidence for the potential effect of statins to reduce the risk of cancer is less clear. Up to 29% of all adults in the United States, or about 70 million people, have high cholesterol, according to the U.S. Centers for Disease Control and Prevention. 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